Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of Caenorhabditis elegans cat
Bioactive Terpenes from Marine Sponges and Their Associated Organisms
In recent years, marine natural products have continued to serve as a pivotal resource for novel drug discovery.Globally, the number of studies focusing on Porifera has been on the rise, underscoring their considerable importance and research value.Marine sponges are prolific producers of a vast array of bioactive compounds, including terpenes, alk
Diallylthiosulfinate (Allicin), a Volatile Antimicrobial from Garlic (Allium sativum), Kills Human Lung Pathogenic Bacteria, Including MDR Strains, as a Vapor
Garlic (Allium sativum) has potent antimicrobial activity due to allicin (diallylthiosulfinate) synthesized by enzyme catalysis in damaged garlic tissues.Allicin gives crushed garlic its characteristic odor and its volatility makes it potentially useful for combating lung infections.Allicin was synthesized (>98% pure) by oxidation of diallyl dis
Neonatal Tetanus in the Department of Child Health Dr. Pirngadi Hospital, Medan in 1983-1984
From January 1983 to December 1984 there had been prospective investigations of neonatal tetanus contracted by newborn infants treated at the Department of Child Health Dr.Pirngadi Hospital Medan.Seventy eight cases (4.28%) contracted neonatal tetanus out of 1821 hospitalized infants.Fifty cases were identified in 1983 and 28 cases in 1984.Fourty n
EVIDENCE IN CRIMINAL JUSTICE: THE IMPORTANCE OF THE EVIDENCE EVALUATION AND ITS CONTROL IN APPEAL
This article discusses important premises related to criminal evidence, aiming to define its function and models for its evaluation in contemporary procedural dogmatics.The problems that guide the development of this research are: 1) what is the role of evidence in criminal procedure?; 2) is the evidence evaluation in judicial decision free? and, 3