Functional analysis of the cathepsin-like cysteine protease genes in adult Brugia malayi using RNA interference.

Cathepsin-like enzymes have been identified as potential targets for drug or vaccine development in many parasites, as their functions appear to be essential in a variety of important biological processes within the host, such as molting, cuticle remodeling, embryogenesis, feeding and immune evasion.Functional analysis of Caenorhabditis elegans cat

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Diallylthiosulfinate (Allicin), a Volatile Antimicrobial from Garlic (Allium sativum), Kills Human Lung Pathogenic Bacteria, Including MDR Strains, as a Vapor

Garlic (Allium sativum) has potent antimicrobial activity due to allicin (diallylthiosulfinate) synthesized by enzyme catalysis in damaged garlic tissues.Allicin gives crushed garlic its characteristic odor and its volatility makes it potentially useful for combating lung infections.Allicin was synthesized (>98% pure) by oxidation of diallyl dis

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